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Methylene Blue (MB) is gaining attention for its potential health benefits, particularly in supporting mitochondrial function and energy production. However, as with any supplement or treatment, understanding the correct dosage is essential. This Methylene Blue dosage guide provides detailed instructions based on the clinical insights of Dr Sarah Myhill, a leading authority in integrative medicine.

Why Dosage Matters with Methylene Blue

Although Methylene Blue is considered very safe when used correctly, it’s crucial to understand that more is not always better. In fact, higher doses of MB may have the opposite effect and potentially cause harm. For this reason, it’s important to adhere to a low-dose approach, especially when first starting out.

Starting Low and Going Slow

Dr Myhill recommends that everyone begins with a conservative dose of 10mg per day, regardless of body weight. This starting point allows your body to adjust gradually while monitoring for any unexpected reactions. The dose can be split into two smaller doses per day – ideally morning and evening – to maintain steady levels in the bloodstream.

To take the dose, simply add the drops to a small glass of water. This creates a blue solution which you then drink. Be aware that temporary blue staining of the teeth and urine is normal and nothing to worry about. The staining is short-lived and not harmful.

Safe Dosage Ranges by Body Weight

The generally accepted safe dosage range is 1–2mg per kg of body weight. Here’s how that translates in practical terms:

A 60kg person would typically take between 60mg (1mg/kg) and 120mg (2mg/kg) per day.
In liquid form, this equates to 6ml to 12ml daily of a 1% solution.
It’s important to increase the dose gradually by 10mg (or 1ml of 1% solution) per week until the desired dose is reached.

Important Safety Notes

Although MB is considered non-toxic in low doses and can even be administered intravenously, high doses (above 15mg/kg) may lead to haemolysis, a condition where red blood cells break down. This risk underscores the importance of sticking to the recommended dosing guidelines and increasing only in small, weekly increments.

Monitoring Your Response

As with any supplement, listen to your body. If you experience any unusual symptoms – such as headaches, nausea, or gastrointestinal discomfort – reduce the dose or pause supplementation and seek medical advice if necessary. However, many users report improved energy, focus, and cognitive clarity at correct doses.

Methylene Blue Dosage Guide: Final Thoughts

This Methylene Blue dosage guide, based on the research and practical experience of Dr Sarah Myhill, provides a safe and effective route for those looking to explore the benefits of MB supplementation. By starting with a low dose and slowly increasing within the 1–2mg/kg range, most people can find a personalised dosage that works for them – without the risks of overuse.

For best results: